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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX1B
All Species:
38.18
Human Site:
S184
Identified Species:
64.62
UniProt:
P61266
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61266
NP_443106.1
288
33245
S184
T
D
D
I
K
M
D
S
Q
M
T
K
Q
A
L
Chimpanzee
Pan troglodytes
XP_001146812
288
32492
S185
A
S
G
I
I
M
D
S
S
I
S
K
Q
A
L
Rhesus Macaque
Macaca mulatta
XP_001103901
336
38070
S232
T
D
D
I
K
M
D
S
Q
M
T
K
Q
A
L
Dog
Lupus familis
XP_547038
348
39606
S192
T
D
D
I
K
M
D
S
Q
M
T
K
Q
A
L
Cat
Felis silvestris
Mouse
Mus musculus
O35526
288
33036
S185
A
S
G
I
I
M
D
S
S
I
S
K
Q
A
L
Rat
Rattus norvegicus
P32851
288
33049
S185
A
S
G
I
I
M
D
S
S
I
S
K
Q
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990405
282
32496
S177
N
D
D
I
K
I
D
S
Q
M
T
K
Q
A
L
Frog
Xenopus laevis
NP_001086322
286
32704
S183
T
S
G
I
I
N
D
S
Q
I
S
R
Q
A
L
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
S184
T
D
D
I
K
M
D
S
Q
M
T
K
Q
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
T188
T
Q
G
I
I
M
E
T
Q
Q
A
K
Q
T
L
Honey Bee
Apis mellifera
XP_393760
291
33455
T189
T
Q
G
I
I
M
E
T
Q
Q
A
K
Q
T
L
Nematode Worm
Caenorhab. elegans
O16000
291
33234
T186
T
Q
G
I
I
T
D
T
Q
Q
A
K
Q
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZQZ8
305
34465
A193
S
E
R
F
L
Q
K
A
I
Q
E
Q
G
R
G
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
A184
F
S
Q
A
L
L
N
A
N
R
R
G
E
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
85.1
75.5
N.A.
84
83.6
N.A.
N.A.
84.7
62.5
96.8
N.A.
68.7
66.3
59.1
N.A.
Protein Similarity:
100
88.1
85.7
78.1
N.A.
94.4
94
N.A.
N.A.
87.5
84
98.2
N.A.
82.1
79
78.3
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
53.3
53.3
N.A.
N.A.
86.6
53.3
100
N.A.
46.6
46.6
46.6
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
66.6
66.6
N.A.
N.A.
93.3
73.3
100
N.A.
60
60
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.8
49.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
8
0
0
0
15
0
0
22
0
0
72
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
36
36
0
0
0
72
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
15
0
0
0
8
0
8
0
0
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
0
0
0
0
0
0
0
0
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
86
50
8
0
0
8
29
0
0
0
0
0
% I
% Lys:
0
0
0
0
36
0
8
0
0
0
0
79
0
0
8
% K
% Leu:
0
0
0
0
15
8
0
0
0
0
0
0
0
0
86
% L
% Met:
0
0
0
0
0
65
0
0
0
36
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
22
8
0
0
8
0
0
65
29
0
8
86
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
8
8
8
0
8
0
% R
% Ser:
8
36
0
0
0
0
0
65
22
0
29
0
0
0
0
% S
% Thr:
58
0
0
0
0
8
0
22
0
0
36
0
0
22
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _